TY - JOUR AU - Guerrero, Fatima AU - Carmona, Andres AU - Obrero, Teresa AU - Jiménez, Maria Jose AU - Soriano, Sagrario AU - Moreno, Juan Antonio AU - Martín-Malo, Alejandro AU - Aljama, Pedro PY - 2020 DO - 10.1038/s41598-020-67574-6 UR - http://hdl.handle.net/10668/4340 T2 - Scientific Reports AB - Protein bound uremic toxins, such as p-cresol, cannot be effectively removed by conventional dialysis techniques and are accumulated in plasma, thus contributing to progression of both chronic kidney disease (CKD) and cardiovascular disease (CVD).... LA - en PB - Springer Nature KW - Endothelial cells KW - Human umbilical vein endothelial cells KW - Uremic toxins KW - Cresols KW - P-cresol KW - Células endoteliales KW - Células endoteliales de la vena umbilical humana KW - Tóxinas urémicas KW - Cresoles KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Movement KW - Medical Subject Headings::Anatomy::Cells::Cellular Structures::Cell Membrane::Cell Membrane Structures::Cell-Derived Microparticles KW - Medical Subject Headings::Anatomy::Cells::Cells, Cultured KW - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Hydrocarbons::Hydrocarbons, Cyclic::Hydrocarbons, Aromatic::Benzene Derivatives::Phenols::Cresols KW - Medical Subject Headings::Anatomy::Cells::Epithelial Cells::Endothelial Cells KW - Medical Subject Headings::Anatomy::Cells::Epithelial Cells::Endothelial Cells::Human Umbilical Vein Endothelial Cells KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Anatomy::Cardiovascular System::Blood Vessels::Microvessels KW - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Toxins, Biological KW - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Up-Regulation KW - Medical Subject Headings::Diseases::Male Urogenital Diseases::Urologic Diseases::Kidney Diseases::Uremia KW - Medical Subject Headings::Diseases::Cardiovascular Diseases::Vascular Diseases TI - Role of endothelial microvesicles released by p-cresol on endothelial dysfunction TY - research article ER -