TY - JOUR AU - Serrano-Saenz, Santiago AU - Palacios, Carmen AU - Delgado-Bellido, Daniel AU - López-Jiménez, Laura AU - Garcia-Diaz, Angel AU - Soto-Serrano, Yolanda AU - Casal, J Ignacio AU - Bartolomé, Rubén A AU - Fernández-Luna, José Luis AU - López-Rivas, Abelardo AU - Oliver, F Javier PY - 2019 DO - 10.1038/s41419-018-1293-3 UR - http://hdl.handle.net/10668/13512 T2 - Cell death & disease AB - Glioblastoma (GBM) is the most common and aggressive brain tumor and is associated with poor prognosis. GBM cells are frequently resistant to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and finding new combinatorial therapies to... LA - en KW - Cell Line, Tumor KW - Drug Resistance, Neoplasm KW - Glioblastoma KW - Humans KW - Proto-Oncogene Proteins c-pim-1 KW - RNA-Binding Proteins KW - Sequestosome-1 Protein KW - TNF-Related Apoptosis-Inducing Ligand KW - Transfection TI - PIM kinases mediate resistance of glioblastoma cells to TRAIL by a p62/SQSTM1-dependent mechanism. TY - research article VL - 10 ER -