RT Journal Article
T1 Mesenchymal stem cells and cell-free preparations for treating atopic dermatitis
A1 Montero-Vilchez, Trinidad
A1 Sanchez-Diaz, Manuel
A1 Montero-Vilchez, Carolina
A1 Sierra-Sanchez, Alvaro
A1 Arias-Santiago, Salvador
K1 Atopic dermatitis
K1 Conditioned medium
K1 Dermatology
K1 Mesenchymal stem cells
K1 Stem cells
K1 Stromal cells
AB Atopic dermatitis (AD) is a chronic cutaneous inflammatory disease caused by an interaction between genetic, immune and epidermal barrier factors. Several treatments can be used to treat this disease but there are patients that do not respond to actual drugs. So, there is a need to develop effective therapies for AD. Mesenchymal stem cells (MSCs) are non-hematopoietic multipotent adult progenitor cells with immunomodulatory power and self-regenerating capacity to repair tissue damage, so they could be a potential effective treatment for AD. MSCs-Conditioned Medium (CM) and MSCs-exosomes are cell-free preparation with molecules secreted by stem cells that could be also beneficial for AD. This viewpoint reviews the actual development of MSCs, MSCs-CM and MSCs-exosomes for treating patients with AD.
PB Tech science press
SN 0327-9545
YR 2022
FD 2022-04-11
LK http://hdl.handle.net/10668/21812
UL http://hdl.handle.net/10668/21812
LA en
NO Montero-Vilchez, Trinidad & Sánchez-Díaz, Manuel & MONTERO-VILCHEZ, CAROLINA & Sierra-Sánchez, Álvaro & ARIAS-SANTIAGO, SALVADOR. (2022). Mesenchymal stem cells and cell-free preparations for treating atopic dermatitis. BIOCELL. 46. 2363-2367.
DS RISalud
RD Apr 20, 2025