TY - JOUR AU - Martínez-Huélamo, Miriam AU - Tulipani, Sara AU - Jáuregui, Olga AU - Valderas-Martínez, Palmira AU - Vallverdú-Queralt, Anna AU - Estruch, Ramón AU - Torrado, Xavier AU - Lamuela-Raventós, Rosa M PY - 2015 DO - 10.3390/molecules201119702 UR - http://hdl.handle.net/10668/2361 T2 - Molecules (Basel, Switzerland) AB - An UHPLC-MS/MS method for the quantification of tomato phenolic metabolites in human fluids was optimized and validated, and then applied in a pilot dietary intervention study with healthy volunteers. A 5-fold gain in speed (3.5 min of total run);... LA - en PB - MDPI KW - Polyphenol metabolites KW - Validation KW - Tomato KW - Sauce KW - Microbiota KW - Metabolites KW - Biosamples KW - Blood KW - Urine KW - Fluidos corporales KW - Cromatografía líquida de alta presión KW - Voluntarios sanos KW - Límite de detección KW - Fenoles KW - Humanos KW - Espectrometría de masas en tándem KW - Medical Subject Headings::Anatomy::Fluids and Secretions::Body Fluids KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Chemistry Techniques, Analytical::Chromatography::Chromatography, Liquid::Chromatography, High Pressure Liquid KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Sensitivity and Specificity::Limit of Detection KW - Medical Subject Headings::Technology, Industry, Agriculture::Food and Beverages::Food::Vegetables::Lycopersicon esculentum KW - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Phenols KW - Medical Subject Headings::Anatomy::Fluids and Secretions::Body Fluids::Blood::Plasma KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Chemistry Techniques, Analytical::Mass Spectrometry::Tandem Mass Spectrometry TI - Sensitive and Rapid UHPLC-MS/MS for the Analysis of Tomato Phenolics in Human Biological Samples. TY - research article ER -