TY - JOUR AU - Jimeno, Sonia AU - Prados-Carvajal, Rosario AU - Fernández-Ávila, María Jesús AU - Silva, Sonia AU - Silvestris, Domenico Alessandro AU - Endara-Coll, Martín AU - Rodríguez-Real, Guillermo AU - Domingo-Prim, Judit AU - Mejías-Navarro, Fernando AU - Romero-Franco, Amador AU - Jimeno-González, Silvia AU - Barroso, Sonia AU - Cesarini, Valeriana AU - Aguilera, Andrés AU - Gallo, Angela AU - Visa, Neus AU - Huertas, Pablo PY - 2021 DO - 10.1038/s41467-021-25790-2 UR - http://hdl.handle.net/10668/18523 T2 - Nature communications AB - The maintenance of genomic stability requires the coordination of multiple cellular tasks upon the appearance of DNA lesions. RNA editing, the post-transcriptional sequence alteration of RNA, has a profound effect on cell homeostasis, but its... LA - en KW - Adenosine Deaminase KW - BRCA1 Protein KW - Cell Line, Tumor KW - DNA KW - DNA Breaks, Double-Stranded KW - DNA Helicases KW - DNA Repair KW - Gene Deletion KW - Genes, Reporter KW - Genomic Instability KW - Green Fluorescent Proteins KW - Homologous Recombination KW - Humans KW - Multifunctional Enzymes KW - Nucleic Acid Hybridization KW - Protein Stability KW - RNA KW - RNA Editing KW - RNA Helicases KW - RNA-Binding Proteins KW - Replication Protein A TI - ADAR-mediated RNA editing of DNA:RNA hybrids is required for DNA double strand break repair. TY - research article VL - 12 ER -