TY  - JOUR
AU  - Nicoletti, Paola
AU  - Barrett, Sarah
AU  - McEvoy, Laurence
AU  - Daly, Ann K
AU  - Aithal, Guruprasad
AU  - Lucena, M Isabel
AU  - Andrade, Raul J
AU  - Wadelius, Mia
AU  - Hallberg, Pär
AU  - Stephens, Camilla
AU  - Bjornsson, Einar S
AU  - Friedmann, Peter
AU  - Kainu, Kati
AU  - Laitinen, Tarja
AU  - Marson, Anthony
AU  - Molokhia, Mariam
AU  - Phillips, Elizabeth
AU  - Pichler, Werner
AU  - Romano, Antonino
AU  - Shear, Neil
AU  - Sills, Graeme
AU  - Tanno, Luciana K
AU  - Swale, Ashley
AU  - Floratos, Aris
AU  - Shen, Yufeng
AU  - Nelson, Matthew R
AU  - Watkins, Paul B
AU  - Daly, Mark J
AU  - Morris, Andrew P
AU  - Alfirevic, Ana
AU  - Pirmohamed, Munir
PY  - 2019
DO  - 10.1002/cpt.1493
UR  - http://hdl.handle.net/10668/13926
T2  - Clinical pharmacology and therapeutics
AB  - Carbamazepine (CBZ) causes life-threating T-cell-mediated hypersensitivity reactions, including serious cutaneous adverse reactions (SCARs) and drug-induced liver injury (CBZ-DILI). In order to evaluate shared or phenotype-specific genetic...
LA  - en
KW  - Adult
KW  - Anaplastic Lymphoma Kinase
KW  - Carbamazepine
KW  - Chemical and Drug Induced Liver Injury
KW  - Drug Hypersensitivity
KW  - Drug Hypersensitivity Syndrome
KW  - Europe
KW  - Female
KW  - Genetic Predisposition to Disease
KW  - Genome-Wide Association Study
KW  - HLA-A Antigens
KW  - HLA-B Antigens
KW  - Humans
KW  - Male
KW  - Phenotype
KW  - Risk Factors
KW  - Stevens-Johnson Syndrome
TI  - Shared Genetic Risk Factors Across Carbamazepine-Induced Hypersensitivity Reactions.
TY  - research article
VL  - 106
ER  -