RT Journal Article
T1 Ambient air pollution and thyroid function in Spanish adults. A nationwide population-based study (Di@bet.es study).
A1 Valdes, Sergio
A1 Doulatram-Gamgaram, Viyey
A1 Maldonado-Araque, Cristina
A1 Lago-Sampedro, Ana
A1 Garcia-Escobar, Eva
A1 Garcia-Serrano, Sara
A1 Garcia-Vivanco, Marta
A1 Garrido-Juan, Luis
A1 Theobald, Mark Richard
A1 Gil, Victoria
A1 Martin-Llorente, Fernando
A1 Ocon, Pilar
A1 Calle-Pascual, Alfonso
A1 Castaño, Luis
A1 Delgado, Elías
A1 Menendez, Edelmiro
A1 Franch-Nadal, Josep
A1 Gaztambide, Sonia
A1 Girbes, Joan
A1 Chaves, F Javier
A1 Galan-Garcia, Jose L
A1 Aguilera-Venegas, Gabriel
A1 Gutierrez-Repiso, Carolina
A1 Fernandez-Garcia, Jose Carlos
A1 Colomo, Natalia
A1 Soriguer, Federico
A1 Garcia-Fuentes, Eduardo
A1 Rojo-Martinez, Gemma
K1 Air pollution
K1 Spain
K1 Thyroid
AB Recent reports have suggested that air pollution may impact thyroid function, although the evidence is still scarce and inconclusive. In this study we evaluated the association of exposure to air pollutants to thyroid function parameters in a nationwide sample representative of the adult population of Spain. The Di@bet.es study is a national, cross-sectional, population-based survey which was conducted in 2008-2010 using a random cluster sampling of the Spanish population. The present analyses included 3859 individuals, without a previous thyroid disease diagnosis, and with negative thyroid peroxidase antibodies (TPO Abs) and thyroid-stimulating hormone (TSH) levels of 0.1-20 mIU/L. Participants were assigned air pollution concentrations for particulate matter  In multivariate linear regression models, there was a highly significant negative correlation between PM2.5 concentrations and both FT4 (p Exposures to PM2.5 in the general population were associated with mild alterations in thyroid function.
PB BioMed Central
YR 2022
FD 2022-08-17
LK http://hdl.handle.net/10668/20322
UL http://hdl.handle.net/10668/20322
LA en
NO Valdés S, Doulatram-Gamgaram V, Maldonado-Araque C, Lago-Sampedro A, García-Escobar E, García-Serrano S, et al. A nationwide population-based study (Di@bet.es study). Environ Health. 2022 Aug 17;21(1):76
NO CIBERDEM (Ministerio de Economía, Industria y Competitividad-ISCIII), Ministerio de Sanidad, Servicios Sociales e Igualdad-ISCIII, Instituto de Salud Carlos III (PI17/02136, PI20/01322), Consejería de Salud y familias (PI-0144-2018), European Regional Development Fund (ERDF) “A way to build Europe”. GRM belongs to the regional Nicolás Monardes research program of the Consejería de Salud (RC-0006-2016; Junta de Andalucía, Spain). CMA is recipient of a “Rio Hortega” research contract (CM19/00186, Instituto de Salud Carlos III). VKDG is recipient of a “Rio Hortega” research contract (CM21/00214, Instituto de Salud Carlos III).
DS RISalud
RD Apr 12, 2025