RT Journal Article
T1 Prevalence of severe esophagitis in Spain. Results of the PRESS study (Prevalence and Risk factors for Esophagitis in Spain: A cross-sectional study).
A1 Piqué, Núria
A1 Ponce, Marta
A1 Garrigues, Vicente
A1 Rodrigo, Luis
A1 Calvo, Félix
A1 de Argila, Carlos Martín
A1 Borda, Fernando
A1 Naranjo, Antonio
A1 Alcedo, Javier
A1 José Soria, María
A1 Rey, Enrique
A1 Bujanda, Luis
A1 Gisbert, Javier P
A1 Suarez, David
A1 Calvet, Xavier
A1 Ponce, Julio
A1 PRESS Study Group, 
K1 Barrett’s esophagus
K1 Endoscopy
K1 gastro-esophageal reflux disease (GERD)
K1 gastrointestinal symptoms
K1 hiatal hernia
K1 nonsteroidal anti-inflammatory drugs (NSAID)
K1 questionnaires
K1 severe esophagitis
AB *N.P. and M.P. contributed equally to this study.The current prevalence of esophagitis in southern Europe is unknown. In addition, the risk factors for reflux esophagitis are not fully understood. The objective of this article is to assess the prevalence and risk factors for esophagitis in Spain. A prospective, observational, cross-sectional, multicenter study (PRESS study) was conducted among 31 gastrointestinal endoscopy units throughout Spain. A total of 1361 patients undergoing upper gastrointestinal endoscopy were enrolled. Sociodemographic, clinical and treatment data were recorded. A total of 95% of patients were Caucasian and 52% were male (mean age: 53 ± 17 years). The most frequent symptoms prompting endoscopy were heartburn (40%), regurgitation (26%) and dysphagia (15%). Fifty-four percent of patients undergoing endoscopy were receiving proton pump inhibitor (PPI) treatment. Esophagitis (mainly mild-moderate) was present in 154 (12.4%) patients. The severe form was recorded in only 11 (0.8%) patients. Multivariate analysis results indicated that the likelihood of esophagitis was higher in men (OR = 1.91, 95% CI = 1.31-2.78), in patients with high GERD-Q scores (OR = 1.256, 95% CI = 1.176-1.343), weight increase (OR = 1.014, 95% CI = 1.003-1.025) and high alcohol consumption (OR = 2.49, 95% CI = 1.16-5.36). Severe esophagitis is a rare finding in the Spanish population. Male gender, high GERD-Q score, weight increase and high alcohol consumption are main risk factors for its appearance.
SN 2050-6406
YR 2015
FD 2015-07-24
LK http://hdl.handle.net/10668/10000
UL http://hdl.handle.net/10668/10000
LA en
DS RISalud
RD Apr 9, 2025