TY - JOUR AU - Martin-Broto, Javier AU - Hindi, Nadia AU - Lopez-Pousa, Antonio AU - Peinado-Serrano, Javier AU - Alvarez, Rosa AU - Alvarez-Gonzalez, Ana AU - Italiano, Antoine AU - Sargos, Paul AU - Cruz-Jurado, Josefina AU - Isern-Verdum, Josep AU - Dolado, Maria Carmen AU - Rincon-Perez, Inmaculada AU - Sanchez-Bustos, Paloma AU - Gutierrez, Antonio AU - Romagosa, Cleofe AU - Morosi, Carlo AU - Grignani, Giovanni AU - Gatti, Marco AU - Luna, Pablo AU - Alastuey, Ignacio AU - Redondo, Andres AU - Belinchon, Belen AU - Martinez-Serra, Jordi AU - Sunyach, Marie-Pierre AU - Coindre, Jean-Michel AU - Dei Tos, Angelo P AU - Romero, Jesus AU - Gronchi, Alessandro AU - Blay, Jean-Yves AU - Moura, David S PY - 2020 DO - 10.1001/jamaoncol.2019.6584 UR - http://hdl.handle.net/10668/15136 T2 - JAMA oncology AB - Active therapeutic combinations, such as trabectedin and radiotherapy, offer potentially higher dimensional response in second-line treatment of advanced soft-tissue sarcomas. Dimensional response can be relevant both for symptom relief and for... LA - en PB - American Medical Association KW - Combined Modality Therapy KW - Dose-Response Relationship, Radiation KW - Humans KW - Middle Aged KW - Spain KW - Trabectedin KW - Adult KW - Aged KW - Disease-Free Survival KW - Dose-Response Relationship, Drug KW - Female KW - France KW - Italy KW - Male KW - Neoplasm Metastasis KW - Sarcoma KW - Spain TI - Assessment of Safety and Efficacy of Combined Trabectedin and Low-Dose Radiotherapy for Patients With Metastatic Soft-Tissue Sarcomas: A Nonrandomized Phase 1/2 Clinical Trial. TY - research article VL - 6 ER -