TY - JOUR AU - Duch, Alba AU - Canal, Berta AU - Barroso, Sonia I AU - García-Rubio, María AU - Seisenbacher, Gerhard AU - Aguilera, Andrés AU - de Nadal, Eulàlia AU - Posas, Francesc PY - 2018 DO - 10.1038/s41467-017-02756-x UR - http://hdl.handle.net/10668/12051 T2 - Nature communications AB - Conflicts between replication and transcription machineries represent a major source of genomic instability and cells have evolved strategies to prevent such conflicts. However, little is known regarding how cells cope with sudden increases of... LA - en KW - Cell Cycle Proteins KW - DNA Replication KW - Escherichia coli KW - Gene Expression Regulation, Fungal KW - Genomic Instability KW - Glucose KW - Hot Temperature KW - Hydrogen Peroxide KW - Osmotic Pressure KW - Oxidative Stress KW - Phosphorylation KW - Protein Serine-Threonine Kinases KW - Recombinant Proteins KW - S Phase KW - Saccharomyces cerevisiae KW - Saccharomyces cerevisiae Proteins KW - Signal Transduction KW - Sodium Chloride KW - Transcription, Genetic TI - Multiple signaling kinases target Mrc1 to prevent genomic instability triggered by transcription-replication conflicts. TY - research article VL - 9 ER -