RT Journal Article T1 Sleeve Gastrectomy and Roux-En-Y Gastric Bypass. Two Sculptors of the Pancreatic Islet A1 Pérez-Arana, Gonzalo-Martín A1 Fernández-Vivero, José A1 Camacho-Ramírez, Alonso A1 Díaz Gómez, Alfredo A1 Bancalero de Los Reyes, José A1 Ribelles-García, Antonio A1 Almorza-Gomar, David A1 Carrasco-Molinillo, Carmen A1 Prada-Oliveira, José-Arturo K1 Sleeve gastrectomy K1 Roux-en-Y gastric bypass K1 Beta-cell K1 Alpha-cell K1 Epsilon-cell K1 Islet K1 Trans-differentiation K1 Carbohydrate metabolism K1 Pancreas K1 Gastrectomía K1 Derivación gástrica K1 Islotes pancreáticos K1 Metabolismo de los hidratos de carbono K1 Páncreas K1 Células K1 Diabetes mellitus AB Several surgical procedures are performed for the treatment of obesity. A main outcome of these procedures is the improvement of type 2 diabetes mellitus. Trying to explain this, gastrointestinal hormone levels and their effect on organs involved in carbohydrate metabolism, such as liver, gut, muscle or fat, have been studied intensively after bariatric surgery. These effects on endocrine-cell populations in the pancreas have been less well studied. We gathered the existing data on these pancreatic-cell populations after the two most common types of bariatric surgery, the sleeve gastrectomy (SG) and the roux-en-Y gastric bypass (RYGB), with the aim to explain the pathophysiological mechanisms underlying these surgeries and to improve their outcome. PB MDPI YR 2021 FD 2021-09-17 LK http://hdl.handle.net/10668/4433 UL http://hdl.handle.net/10668/4433 LA en NO Pérez-Arana GM, Fernández-Vivero J, Camacho-Ramírez A, Díaz Gómez A, Bancalero de Los Reyes J, Ribelles-García A, et al. Sleeve Gastrectomy and Roux-En-Y Gastric Bypass. Two Sculptors of the Pancreatic Islet. J Clin Med. 2021 Sep 17;10(18):4217. DS RISalud RD Apr 6, 2025