TY - JOUR AU - Castaño-Amores, Celia AU - Díaz-Villamarín, Xando AU - Pérez-Gutiérrez, Ana María AU - Antúnez-Rodríguez, Alba AU - Pozo-Agundo, Ana AU - Moreno-Escobar, Eduardo AU - Sánchez-Ramos, Jesús Gabriel AU - Martínez-González, Luis Javier AU - Dávila-Fajardo, Cristina Lucía PY - 2021 DO - 10.1016/j.biopha.2021.112069 SN - 0753-3322 UR - http://hdl.handle.net/10668/4062 T2 - Biomedicine & Pharmacotherapy AB - β-blockers are commonly prescribed to treat multiple cardiovascular (CV) diseases, but, frequently, adverse drug reactions and intolerance limit their use in clinical practice. Interindividual variability in response to β-blockers may be explained by... LA - en PB - Elsevier KW - Bisoprolol KW - Pharmacogenetic KW - β-blockers KW - Cardiovascular diseases KW - Personalized medicine KW - Farmacogenética KW - Anticuerpos bloqueadores KW - Enfermedades cardiovasculares KW - Medicina de precisión KW - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Neurotransmitter Agents::Adrenergic Agents::Adrenergic Antagonists::Adrenergic... KW - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Alcohols::Amino Alcohols::Propanolamines::Phenoxypropanolamines::Bisoprolol KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Vital Signs::Blood Pressure KW - Medical Subject Headings::Diseases::Cardiovascular Diseases KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Polymorphism, Genetic::Polymorphism, Single Nucleotide KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Receptors, Cell Surface::Receptors, Biogenic Amine::Receptors, Catecholamine::Receptors, Adrenergic::Receptors, Adrenergic,... KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis::Treatment Outcome KW - Medical Subject Headings::Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Pharmacology::Pharmacogenetics TI - Pharmacogenetic polymorphisms affecting bisoprolol response TY - research article ER -