TY - JOUR AU - González-Serna, David AU - Carmona, Elio G AU - Ortego-Centeno, Norberto AU - Simeón, Carmen P AU - Solans, Roser AU - Hernández-Rodríguez, José AU - Tolosa, Carlos AU - Castañeda, Santos AU - Narváez, Javier AU - Martinez-Valle, Ferran AU - European GCA Consortium AU - European Scleroderma Group AU - Witte, Torsten AU - Neumann, Thomas AU - Holle, Julia AU - Beretta, Lorenzo AU - Boiardi, Luigi AU - Emmi, Giacomo AU - Cimmino, Marco A AU - Vaglio, Augusto AU - Herrick, Ariane L AU - Denton, Christopher P AU - Salvarani, Carlo AU - Cid, María C AU - Morgan, Ann W AU - Fonseca, Carmen AU - González-Gay, Miguel A AU - Martín, Javier AU - Márquez, Ana PY - 2018 DO - 10.1371/journal.pone.0209343 UR - https://hdl.handle.net/10668/26069 T2 - PloS one AB - The TNFSF13B (TNF superfamily member 13b) gene encodes BAFF, a cytokine with a crucial role in the differentiation and activation of B cells. An insertion-deletion variant (GCTGT→A) of this gene, leading to increased levels of BAFF, has been recently... LA - en KW - Adult KW - Aged KW - Aged, 80 and over KW - B-Cell Activating Factor KW - Biopsy KW - Case-Control Studies KW - Cohort Studies KW - Europe KW - Female KW - Gene Regulatory Networks KW - Genetic Predisposition to Disease KW - Genotyping Techniques KW - Giant Cell Arteritis KW - Humans KW - INDEL Mutation KW - Male KW - Middle Aged KW - Polymorphism, Single Nucleotide KW - Scleroderma, Systemic TI - A TNFSF13B functional variant is not involved in systemic sclerosis and giant cell arteritis susceptibility. TY - research article VL - 13 ER -