RT Journal Article
T1 Activities of gemifloxacin and five other antimicrobial agents against Listeria monocytogenes and coryneform bacteria isolated from clinical samples
A1 Martínez-Martínez, L
A1 Joyanes, P
A1 Suárez, A I
A1 Perea, E J
K1 Antibacterianos
K1 Corynebacterium
K1 Listeria monocytogenes
K1 Naftiridinas
K1 Fluoroquinolonas
AB The in vitro activities of gemifloxacin, ciprofloxacin, ampicillin, doxycycline, gentamicin, and vancomycin were evaluated against 15 Listeria monocytogenes strains and 205 coryneform bacteria isolated from clinical samples. The percentages of strains inhibited by gemifloxacin at 0.5 microg/ml were 100% (L. monocytogenes), 93.3% (Brevibacterium spp.), 90% (Corynebacterium minutissimum), 42.5% (Corynebacterium amycolatum), 20% (Corynebacterium striatum), 12.5% (Corynebacterium jeikeium), and 10% (Corynebacterium urealyticum). One hundred percent of the L. monocytogenes strains were inhibited by 0.25 microg of gemifloxacin per ml, whereas 0% of the strains were inhibited by 0.25 microg of ciprofloxacin per ml. Vancomycin at 2 microg/ml inhibited all strains. Doxycycline and gentamicin at 4 microg/ml inhibited 94 and 49% of the strains, respectively, while ampicillin at 0.5, 2, and 8 microg/ml inhibited 24, 61, and 66% of the strains, respectively. It is concluded that gemifloxacin shows good in vitro activity against L. monocytogenes and coryneform bacteria except C. jeikeium and C. urealyticum.
PB American Society for Microbiology
SN 0095-1137
YR 2001
FD 2001-08
LK http://hdl.handle.net/10668/2617
UL http://hdl.handle.net/10668/2617
LA en
NO Martínez-Martínez L, Joyanes P, Suárez AI, Perea EJ. Activities of gemifloxacin and five other antimicrobial agents against Listeria monocytogenes and coryneform bacteria isolated from clinical samples. Antimicrob Agents Chemother. 2001;45(8):2390-2.
NO This study was supported by a grant from SmithKline Beecham Pharmaceuticals
DS RISalud
RD Apr 11, 2025