TY - JOUR AU - Herbst, Roy S AU - Arkenau, Hendrik-Tobias AU - Santana-Davila, Rafael AU - Calvo, Emiliano AU - Paz-Ares, Luis AU - Cassier, Philippe A AU - Bendell, Johanna AU - Penel, Nicolas AU - Krebs, Matthew G AU - Martin-Liberal, Juan AU - Isambert, Nicolas AU - Soriano, Andres AU - Wermke, Martin AU - Cultrera, Jennifer AU - Gao, Ling AU - Widau, Ryan C AU - Mi, Gu AU - Jin, Jin AU - Ferry, David AU - Fuchs, Charles S AU - Petrylak, Daniel P AU - Chau, Ian PY - 2019 DO - 10.1016/S1470-2045(19)30458-9 UR - http://hdl.handle.net/10668/14239 T2 - The Lancet. Oncology AB - Pre-clinical and clinical evidence suggests that simultaneous blockade of VEGF receptor-2 (VEGFR-2) and PD-1 or PD-L1 enhances antigen-specific T-cell migration, antitumour activity, and has favourable toxicity. In this study, we aimed to assess the... LA - en KW - Adenocarcinoma KW - Aged KW - Antibodies, Monoclonal, Humanized KW - Antineoplastic Agents, Immunological KW - Antineoplastic Combined Chemotherapy Protocols KW - Carcinoma, Non-Small-Cell Lung KW - Carcinoma, Transitional Cell KW - Dose-Response Relationship, Drug KW - Esophageal Neoplasms KW - Female KW - Humans KW - Lung Neoplasms KW - Male KW - Middle Aged KW - Stomach Neoplasms TI - Ramucirumab plus pembrolizumab in patients with previously treated advanced non-small-cell lung cancer, gastro-oesophageal cancer, or urothelial carcinomas (JVDF): a multicohort, non-randomised, open-label, phase 1a/b trial. TY - research article VL - 20 ER -