RT Journal Article
T1 Validation of a new proposal to avoid donor resuscitation in controlled donation after circulatory death with normothermic regional perfusion.
A1 Perez-Villares, Jose Miguel
A1 Rubio, Juan José
A1 Del Río, Francisco
A1 Miñambres, Eduardo
K1 Cerebral resuscitation
K1 Controlled donation after circulatory death
K1 Normothermic regional perfusion
AB The use of abdominal normothermic regional perfusion (nRP) and premortem interventions in controlled donation after circulatory death (cDCD) may represent a significant advance to increase the number and quality of grafts recovered in cDCD. The main limitation for the widespread acceptance of nRP in cDCD is the concerns of restoring circulation to the brain once death has been declared should the thoracic aorta not be adequately blocked. We describe and validate a specific methodology to ensure an appropriate blocking of the thoracic aorta in a multicenter study using this technique. A total of 78 procedures with premortem cannulation and abdominal nRP were performed in four different hospitals. No case of heart or brain resuscitation was observed after nRP CONCLUSION: The use of premortem interventions before nRP and the aortic occlusion balloon may increase the number of grafts recovered in cDCD. Our proposed methodology avoids the ethical problem of resuscitation by guaranteeing that circulation to the heart and brain is not restored after nRP.
YR 2017
FD 2017-06-04
LK http://hdl.handle.net/10668/11278
UL http://hdl.handle.net/10668/11278
LA en
DS RISalud
RD Apr 10, 2025