RT Journal Article
T1 Validity of four commercially available metabolic carts for assessing resting metabolic rate and respiratory exchange ratio in non-ventilated humans.
A1 Alcantara, J M A
A1 Galgani, J E
A1 Jurado-Fasoli, L
A1 Dote-Montero, M
A1 Merchan-Ramirez, E
A1 Ravussin, E
A1 Ruiz, J R
A1 Sanchez-Delgado, G
K1 Basal metabolic rate
K1 Indirect calorimetry
K1 Reliability
AB The validity of most commercially available metabolic cart is mostly unknown. Thus, we aimed to determine the accuracy, precision, within-subject reproducibility, and concordance of RMR and RER measured by four commercially available metabolic carts [Cosmed Q-NRG, Vyaire Vyntus CPX, Maastricht Instruments Omnical, and Medgraphics Ultima CardiO2]. Further, we studied whether a previously proposed simulation-based post-calorimetric calibration of cart readouts [individual calibration control evaluation (ICcE)] modify the RMR and RER reproducibility and concordance. Three experiments simulating different RMR and RER by controlled pure gas (N2 and CO2) infusions were conducted on 5 non-consecutive days. Moreover, 30-min methanol burns were performed on 3 non-consecutive days. Lastly, the RMR and RER of 29 young non-ventilated adults (11 women; 25 ± 4 years-old; BMI: 24.1 ± 3.2 kg/m2) were assessed twice using each instrument, 24 hours apart, under standardized conditions. The Omnical presented the lowest measurement error for RER (Omnical = 1.7 ± 0.9%; Vyntus = 4.5 ± 2.0%; Q-NRG = 6.6 ± 1.9%; Ultima = 6.8 ± 6.5%) and EE (Omnical = 1.5 ± 0.5%; Q-NRG = 2.5 ± 1.3%; Ultima = 10.7 ± 11.0%; Vyntus = 13.8 ± 5.0%) in all in vitro experiments (controlled pure gas infusions and methanol burns). In humans, the 4 metabolic carts provided discordant RMR and RER estimations (all P  The 4 metabolic carts provided discordant measurements of RMR and RER. Overall, the Omnical provides more accurate and precise estimations of RMR and RER than the Q-NRG, Vyntus and Ultima CardiO2, and might be considered the best for assessing RMR and RER in non-ventilated humans. Finally, our results do not support the use of an ICcE procedure.
PB Elsevier BV
YR 2022
FD 2022-05-18
LK http://hdl.handle.net/10668/22112
UL http://hdl.handle.net/10668/22112
LA en
NO Alcantara JMA, Galgani JE, Jurado-Fasoli L, Dote-Montero M, Merchan-Ramirez E, Ravussin E, et al. Validity of four commercially available metabolic carts for assessing resting metabolic rate and respiratory exchange ratio in non-ventilated humans. Clin Nutr. 2022 Mar;41(3):746-754
NO Supported by the Spanish Ministry of Economy and Competitiveness via Retos de la Sociedad grant DEP2016-79512-R (to JRR), and European Regional Development Fund (ERDF); Spanish Ministry of Education grant ( FPU15 /04059 to JMAA; FPU19/01609 to LJ-F; and FPU18/03357 to MD-M); the University of Granada Plan Propio de Investigación 2016-Excellence actions: Unit of Excellence on Exercise and Health (to JRR) - Plan Propio de Investigación 2018 Programa Contratos-Puente and Programa Perfeccionamiento de Doctores (to GS-D); Junta de Andalucía, Consejería de Conocimiento, Investigación y Universidades grant SOMM17/6107/UGR (to JRR) via the ERDF; and the Fundación Alfonso Martín Escudero (to GS-D); Funding for open access charge: Universidad de Granada / CBUA.
DS RISalud
RD Apr 8, 2025