TY - JOUR AU - Aldea, Mihaela AU - Lam, Laurent AU - Orillard, Emeline AU - Llacer Perez, Casilda AU - Saint-Ghislain, Mathilde AU - Gravis, Gwenaelle AU - Flechon, Aude AU - Roubaud, Guilhem AU - Barthelemy, Philippe AU - Ricci, Francesco AU - Priou, Frank AU - Neviere, Zoe AU - Beaufils, Mathilde AU - Laguerre, Brigitte AU - Hardy, Anne-Claire AU - Helissey, Carole AU - Ratta, Raffaele AU - Borchiellini, Delphine AU - Pobel, Cedric AU - Joly, Florence AU - Castro, Elena AU - Thiery-Vuillemin, Antoine AU - Baciarello, Giulia AU - Fizazi, Karim PY - 2021 DO - 10.1016/j.ejca.2021.09.029 SN - 0959-8049 UR - https://hdl.handle.net/10668/26859 T2 - European journal of cancer AB - Background: Cabazitaxel was shown to improve overall survival (OS) in patients with metastatic castration-resistant prostate cancer (mCRPC) after abiraterone/enzalutamine and docetaxel failure, though benefit by the presence of DNA damage repair (DDR)... LA - en PB - Elsevier sci ltd KW - DNA damage repair KW - BRCA KW - Cabazitaxel KW - PARP inhibitors KW - mCRPC KW - Treatment outcomes KW - Gene-mutations KW - Phase-iii TI - Cabazitaxel activity in men with metastatic castration-resistant prostate cancer with and without DNA damage repair defects TY - research article VL - 159 ER -