RT Journal Article
T1 Cytomegalovirus as a Driver of Excess Cardiovascular Mortality in Rheumatoid Arthritis: A Red Herring or a Smoking Gun?
A1 Pera, Alejandra
A1 Broadley, Iain
A1 Davies, Kevin A
A1 Kern, Florian
K1 CD4 T-lymphocytes
K1 Atherosclerosis
K1 Cytomegalovirus
K1 Cytotoxicity
K1 Inflammation
K1 Rheumatoid arthritis
AB Rheumatoid arthritis (RA) is the most common in-flammatory arthritis worldwide. Apart from its well-known manifestations involving the joints (eg, deformity,swelling, and synovial inflammation), there are wide-spread, extra-articular manifestations that also involve thecardiovascular system. 1 The consequences of cardiovascu-lar involvement are often serious; cerebrovascular disease,ischemic heart disease, and cardiovascular disease (CVD)–associated death are ≤50% higher in the context of RAleading to a reduction of life-expectancy in these patientsof 3 to 10 years compared with the general population. 1 Todate, no satisfactory explanation of this phenomenon hasbeen found, or maybe, it has been overlooked
PB Lippincott Williams & Wilkins
YR 2017
FD 2017
LK http://hdl.handle.net/10668/10790
UL http://hdl.handle.net/10668/10790
LA en
NO Pera A, Broadley I, Davies KA, Kern F. Cytomegalovirus as a Driver of Excess Cardiovascular Mortality in Rheumatoid Arthritis: A Red Herring or a Smoking Gun? Circ Res. 2017 Jan 20;120(2):274-277
DS RISalud
RD Apr 10, 2025