%0 Journal Article
%A Pera, Alejandra
%A Broadley, Iain
%A Davies, Kevin A
%A Kern, Florian
%T Cytomegalovirus as a Driver of Excess Cardiovascular Mortality in Rheumatoid Arthritis: A Red Herring or a Smoking Gun?
%D 2017
%U http://hdl.handle.net/10668/10790
%X Rheumatoid arthritis (RA) is the most common in-flammatory arthritis worldwide. Apart from its well-known manifestations involving the joints (eg, deformity,swelling, and synovial inflammation), there are wide-spread, extra-articular manifestations that also involve thecardiovascular system. 1 The consequences of cardiovascu-lar involvement are often serious; cerebrovascular disease,ischemic heart disease, and cardiovascular disease (CVD)–associated death are ≤50% higher in the context of RAleading to a reduction of life-expectancy in these patientsof 3 to 10 years compared with the general population. 1 Todate, no satisfactory explanation of this phenomenon hasbeen found, or maybe, it has been overlooked
%K CD4 T-lymphocytes
%K Atherosclerosis
%K Cytomegalovirus
%K Cytotoxicity
%K Inflammation
%K Rheumatoid arthritis
%~