TY - JOUR AU - Boza-Serrano, Antonio AU - Vrillon, Agathe AU - Minta, Karolina AU - Paulus, Agnes AU - Camprubí-Ferrer, Lluís AU - Garcia, Megg AU - Andreasson, Ulf AU - Antonell, Anna AU - Wennström, Malin AU - Gouras, Gunnar AU - Dumurgier, Julien AU - Cognat, Emmanuel AU - Molina-Porcel, Laura AU - Balasa, Mircea AU - Vitorica, Javier AU - Sánchez-Valle, Raquel AU - Paquet, Claire AU - Venero, Jose Luis AU - Blennow, Kaj AU - Deierborg, Tomas PY - 2022 DO - 10.1007/s00401-022-02469-6 UR - http://hdl.handle.net/10668/19953 T2 - Acta neuropathologica AB - Galectin-3 (Gal-3) is a beta-galactosidase binding protein involved in microglial activation in the central nervous system (CNS). We previously demonstrated the crucial deleterious role of Gal-3 in microglial activation in Alzheimer's disease (AD).... LA - en KW - Alzheimer Disease KW - Amyloid beta-Peptides KW - Animals KW - Biomarkers KW - Brain KW - Chitinase-3-Like Protein 1 KW - GAP-43 Protein KW - Galectin 3 KW - Humans KW - Mice KW - Neurogranin KW - Plaque, Amyloid KW - beta-Galactosidase KW - tau Proteins TI - Galectin-3 is elevated in CSF and is associated with Aβ deposits and tau aggregates in brain tissue in Alzheimer's disease. TY - research article VL - 144 ER -