RT Journal Article
T1 Experience in neuromuscular diseases in children and adolescents and their comorbidities in a tertiary hospital
A1 Gascón-Navarro, J A.
A1 De La Torre-Aguilar, M J.
A1 Fernández-Ramos, J A.
A1 Torres-Borrego, J.
A1 Pérez-Navero, J L.
K1 Neuromuscular diseases
K1 Tertiary hospital
K1 Noninvasive ventilation
K1 Respiration, artificial
K1 Respiratory insufficiency
K1 Enfermedades neuromusculares
K1 Centros de asistencia terciaria
K1 Ventilación no invasiva
K1 Respiración artificial
K1 Insuficiencia respiratoria
AB Introduction: Neuromuscular diseases include a large group of heterogeneous and rare pathologies that affect different components of the motor unit. It is essential to optimize resources to know the prevalence of comorbidities in the most frequent groups to establish an early multidisciplinary approach in a specialized setting. Patients and methods: Retrospective descriptive study of pediatric and adolescent patients with neuromuscular diseases (NMDs). The Inclusion criteria were NMDs patients with motor neuron involvement divided into three groups, depending on the affected component of the motor unit. Group I: involvement of the motor neuron; Group II: peripheral neuropathies; Group III: myopathies. Demographic variables, association with comorbidities, need for respiratory support, and rehabilitative treatment were collected in each group. Results: Ninety-six patients who met the inclusion criteria were studied. In group I, when compared to the other two groups, a higher incidence of scoliosis (68.3%, p = 0.011), deformity of the rib cage (31.3%, p = 0.0001), chronic respiratory insufficiency (62.5%, p = 0.001) and bronchial aspiration (12.5%, p = 0.03) was detected. In this group, 50%of the patients required non-invasive mechanical ventilation (p = 0.0001). The in-hospital requirement for respiratory physiotherapy was higher in group I (75%, p = 0.001). We observed a higher incidence of scoliosis in Group III compared to Group II. Conclusions: Neuromuscular diseases with motor neuron involvement present more comorbidities and require an early approach after diagnosis to improve prognosis.
PB BioMed Central
SN 1824-7288
YR 2021
FD 2021-11-16
LK http://hdl.handle.net/10668/4337
UL http://hdl.handle.net/10668/4337
LA en
NO Gascón-Navarro JA, De La Torre-Aguilar MJ, Fernández-Ramos JA, Torres-Borrego J, Pérez-Navero JL. Experience in neuromuscular diseases in children and adolescents and their comorbidities in a tertiary hospital. Ital J Pediatr. 2021 Nov 16;47(1):228
DS RISalud
RD Apr 11, 2025