RT Journal Article
T1 Effect of omega-3 fatty acids on hypoalbuminemia in acute heart failure patients with increased inflammatory activity
A1 Bonilla Palomas, Juan Luis
A1 Gamez Lopez, Antonio Luis
A1 Moreno Conde, Mirian
A1 Lopez Ibanez, Maria Cristina
A1 Moreno Villar, Maria Amparo
K1 Heart failure
K1 Hypoalbuminemia
K1 Inflammatory activity
K1 Omega-3 polyunsaturated fatty acids
K1 Clinical trial
K1 Polyunsaturated fatty-acids
K1 Levels predict survival
K1 Necrosis-factor-alpha
K1 Serum-albumin
K1 European-society
K1 Protein
K1 Activation
K1 Receptors
K1 Mortality
K1 Diagnosis
AB Introduction: inflammatory activity (IA) is a cause of hypoalbuminemia in patients with acute heart failure (AHF).Objectives: the main objective of this study was to evaluate whether an AI modulator treatment contributes to correcting albuminemia in this context.Methods: in this clinical trial 43 patients with AHF, hypoalbuminemia (serum albumin = 25 mg/l] were randomly assigned to receive omega-3 fatty acids (4 g daily) or placebo for 4 weeks. Albuminemia and CRP were reassessed at weeks 1 and 4. An analysis of variance for repeated measures was performed.Results: mean age was 75.6 +/- 8.8 years, 72.1 % were male, and the most frequent etiology was ischemic (46.5 %). The two groups were homogeneous in their baseline characteristics. A significant increase in albumin concentration was found at week 4 from baseline (p for the effect of time
PB Aran ediciones, s l
SN 0212-1611
YR 2021
FD 2021-09-01
LK https://hdl.handle.net/10668/26573
UL https://hdl.handle.net/10668/26573
LA es
DS RISalud
RD Mar 18, 2025