%0 Journal Article
%A Bonilla Palomas, Juan Luis
%A Gamez Lopez, Antonio Luis
%A Moreno Conde, Mirian
%A Lopez Ibanez, Maria Cristina
%A Moreno Villar, Maria Amparo
%T Effect of omega-3 fatty acids on hypoalbuminemia in acute heart failure patients with increased inflammatory activity
%D 2021
%@ 0212-1611
%U https://hdl.handle.net/10668/26573
%X Introduction: inflammatory activity (IA) is a cause of hypoalbuminemia in patients with acute heart failure (AHF).Objectives: the main objective of this study was to evaluate whether an AI modulator treatment contributes to correcting albuminemia in this context.Methods: in this clinical trial 43 patients with AHF, hypoalbuminemia (serum albumin = 25 mg/l] were randomly assigned to receive omega-3 fatty acids (4 g daily) or placebo for 4 weeks. Albuminemia and CRP were reassessed at weeks 1 and 4. An analysis of variance for repeated measures was performed.Results: mean age was 75.6 +/- 8.8 years, 72.1 % were male, and the most frequent etiology was ischemic (46.5 %). The two groups were homogeneous in their baseline characteristics. A significant increase in albumin concentration was found at week 4 from baseline (p for the effect of time
%K Heart failure
%K Hypoalbuminemia
%K Inflammatory activity
%K Omega-3 polyunsaturated fatty acids
%K Clinical trial
%K Polyunsaturated fatty-acids
%K Levels predict survival
%K Necrosis-factor-alpha
%K Serum-albumin
%K European-society
%K Protein
%K Activation
%K Receptors
%K Mortality
%K Diagnosis
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