%0 Journal Article %A Bonilla Palomas, Juan Luis %A Gamez Lopez, Antonio Luis %A Moreno Conde, Mirian %A Lopez Ibanez, Maria Cristina %A Moreno Villar, Maria Amparo %T Effect of omega-3 fatty acids on hypoalbuminemia in acute heart failure patients with increased inflammatory activity %D 2021 %@ 0212-1611 %U https://hdl.handle.net/10668/26573 %X Introduction: inflammatory activity (IA) is a cause of hypoalbuminemia in patients with acute heart failure (AHF).Objectives: the main objective of this study was to evaluate whether an AI modulator treatment contributes to correcting albuminemia in this context.Methods: in this clinical trial 43 patients with AHF, hypoalbuminemia (serum albumin = 25 mg/l] were randomly assigned to receive omega-3 fatty acids (4 g daily) or placebo for 4 weeks. Albuminemia and CRP were reassessed at weeks 1 and 4. An analysis of variance for repeated measures was performed.Results: mean age was 75.6 +/- 8.8 years, 72.1 % were male, and the most frequent etiology was ischemic (46.5 %). The two groups were homogeneous in their baseline characteristics. A significant increase in albumin concentration was found at week 4 from baseline (p for the effect of time %K Heart failure %K Hypoalbuminemia %K Inflammatory activity %K Omega-3 polyunsaturated fatty acids %K Clinical trial %K Polyunsaturated fatty-acids %K Levels predict survival %K Necrosis-factor-alpha %K Serum-albumin %K European-society %K Protein %K Activation %K Receptors %K Mortality %K Diagnosis %~