TY - JOUR AU - Sáez-Martínez, Prudencio AU - Jiménez-Vacas, Juan M. AU - León-González, Antonio J. AU - Herrero-Aguayo, Vicente AU - Montero Hidalgo, Antonio J. AU - Gómez-Gómez, Enrique AU - Sánchez-Sánchez, Rafael AU - Requena-Tapia, María J. AU - Castaño, Justo P. AU - Gahete, Manuel D. AU - Luque, Raúl M. PY - 2020 DO - 10.3390/jcm9061703 UR - http://hdl.handle.net/10668/3883 T2 - Journal of Clinical Medicine AB - Certain components of the somatostatin-system play relevant roles in Prostate Cancer (PCa), whose most aggressive phenotype (Castration-Resistant-PCa (CRPC)) remains lethal nowadays. However, neuronostatin and the G protein-coupled receptor 107... LA - en PB - MDPI KW - Prostate cancer KW - Castration resistant prostate cancer KW - Neuronostatin KW - G protein-coupled receptor GPR107 KW - Diagnostic/prognostic biomarker KW - Therapeutic target KW - Somatostatin-system KW - Splicing KW - Neoplasias de la próstata KW - Neoplasias de la próstata resistentes a la castración KW - Somatostatina KW - Andalucía KW - Medical Subject Headings::Check Tags::Male KW - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Urogenital Neoplasms::Genital Neoplasms, Male::Prostatic Neoplasms::Prostatic Neoplasms, Castration-Resistant KW - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Androgens KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Neoplasm Proteins::Oncogene Proteins::Proto-Oncogene Proteins::Proto-Oncogene Proteins c-akt KW - Medical Subject Headings::Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Peptide Hormones::Ghrelin KW - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Antigens::Antigens, Nuclear::Ki-67 Antigen KW - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Peptide Hydrolases::Endopeptidases::Metalloendopeptidases::Collagenases::Matrix Metalloproteinase 9 KW - Medical Subject Headings::Anatomy::Urogenital System::Genitalia::Genitalia, Male::Prostate KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis KW - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Down-Regulation KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Growth Processes::Cell Proliferation KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Receptors, Cell Surface::Receptors, G-Protein-Coupled KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Receptors, Cell Surface::Receptors, G-Protein-Coupled::Receptors, Somatostatin KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures, Operative::Urogenital Surgical Procedures::Castration KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Phenotype KW - Medical Subject Headings::Information Science::Information Science::Computing Methodologies::Artificial Intelligence KW - Medical Subject Headings::Geographical Locations::Geographic Locations::Europe::Spain TI - Unleashing the Diagnostic, Prognostic and Therapeutic Potential of the Neuronostatin/GPR107 System in Prostate Cancer TY - research article ER -