RT Journal Article
T1 The TREX1 Dinosaur Bites the Brain through the LINE.
A1 García Pérez, José Luis
A1 Alarcón-Riquelme, Marta E
AB In this issue of Cell Stem Cell, Thomas et al. (2017) define the nature of accumulated ssDNA present in the neuron and astrocyte cytoplasm of TREX1 mutated stem cell-derived organoids. Accumulated ssDNAs are derived from LINE-1 endogenous retroelements, providing new clues as to the development of Aicardi-Goutières syndrome in the neural system.
YR 2017
FD 2017
LK http://hdl.handle.net/10668/11566
UL http://hdl.handle.net/10668/11566
LA en
DS RISalud
RD Apr 7, 2025