%0 Journal Article
%A García Pérez, José Luis
%A Alarcón-Riquelme, Marta E
%T The TREX1 Dinosaur Bites the Brain through the LINE.
%D 2017
%U http://hdl.handle.net/10668/11566
%X In this issue of Cell Stem Cell, Thomas et al. (2017) define the nature of accumulated ssDNA present in the neuron and astrocyte cytoplasm of TREX1 mutated stem cell-derived organoids. Accumulated ssDNAs are derived from LINE-1 endogenous retroelements, providing new clues as to the development of Aicardi-Goutières syndrome in the neural system.
%~