RT Journal Article T1 The impact of tooth loss on cognitive function A1 Galindo-Moreno, Pablo A1 Lopez-Chaichio, Lucia A1 Padial-Molina, Miguel A1 Avila-Ortiz, Gustavo A1 O'Valle, Francisco A1 Ravida, Andrea A1 Catena, Andres K1 Oral health K1 Mastication K1 Cognitive dysfunction K1 Dementia K1 Aging K1 Dental prosthesis K1 Association K1 Impairment K1 Dementia K1 Diseases K1 Health AB Objective To investigate if there is epidemiological evidence of an association between edentulism and cognitive decline beside that currently available from limited sample-sized case series and cross-sectional studies considering limited co-variables. Materials and methods Data from two USA national health surveys [NHIS 2014-2017 and NHANES 2005-2018] were analyzed using multinomial logistic regression to study the impact of type of edentulism and number of remaining teeth on memory and concentration problems. Age, gender, socioeconomic status, education level, cardiovascular health index, body mass index, exercise, alcohol, smoking habits, and anxiety and depression were used as covariates. Results The combined population sample was 102,291 individuals. Age, socioeconomic status, educational level, anxiety and depression levels, and edentulism showed the highest odds ratios for cognitive decline. Number of teeth present in the mouth was found to be a predictor of cognitive status. This association showed a gradient effect, so that the lower the number of teeth, the greater the risk of exhibiting cognitive decline. Conclusions Edentulism was found among the higher ORs for cognitive impairment. PB Springer heidelberg SN 1432-6981 YR 2021 FD 2021-12-08 LK https://hdl.handle.net/10668/28065 UL https://hdl.handle.net/10668/28065 LA en DS RISalud RD Apr 10, 2025