RT Journal Article
T1 Combined LC/UV/MS and NMR Strategies for the Dereplication of Marine Natural Products.
A1 Pérez-Victoria, Ignacio
A1 Martín, Jesús
A1 Reyes, Fernando
AB Drug discovery from marine natural products has experienced a revival since the beginning of this century. To be successful in this field, rapid dereplication (identification of already known bioactive compounds) is essential in order to assess the chemical novelty of crude extracts and their fractions. Access to the appropriate state-of-the-art analytical instrumentation and to suitable databases is a fundamental requirement in such a task. A brief survey of the most robust LC/UV/MS- and NMR-based approaches employed for marine natural product dereplication is presented alongside a description of the procedures followed to achieve this goal in our research group.
YR 2016
FD 2016-03-22
LK http://hdl.handle.net/10668/9936
UL http://hdl.handle.net/10668/9936
LA en
DS RISalud
RD Apr 6, 2025