TY - JOUR AU - Bartolome, Fernando AU - Antequera, Desiree AU - Tavares, Eva AU - Pascual, Consuelo AU - Maldonado, Rosario AU - Camins, Antoni AU - Carro, Eva PY - 2017 DO - 10.1186/s12974-017-0800-2 UR - http://hdl.handle.net/10668/10825 T2 - Journal of neuroinflammation AB - The multiligand receptor megalin controls the brain uptake of a number of ligands, including insulin and leptin. Despite the role of megalin in the transport of these metabolically relevant hormones, the role of megalin at the blood-brain-barrier... LA - en KW - Blood–brain barrier KW - Hyperleptinemia KW - Inflammation KW - Leptin resistance KW - Megalin KW - Obesity KW - Age Factors KW - Animals KW - Blood-Brain Barrier KW - Brain KW - Cytokines KW - Disease Models, Animal KW - Doublecortin Domain Proteins KW - Eating KW - Encephalitis KW - Endothelial Cells KW - Glial Fibrillary Acidic Protein KW - Low Density Lipoprotein Receptor-Related Protein-2 KW - Male KW - Mice KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Microtubule-Associated Proteins KW - Mitochondria KW - Neuropeptides KW - Obesity KW - Phosphopyruvate Hydratase KW - STAT3 Transcription Factor TI - Obesity and neuroinflammatory phenotype in mice lacking endothelial megalin. TY - research article VL - 14 ER -