RT Journal Article T1 Management of patients with chronic rhinosinusitis during the COVID-19 pandemic-An EAACI position paper. A1 Klimek, Ludger A1 Jutel, Marek A1 Bousquet, Jean A1 Agache, Ioana A1 Akdis, Cezmi A A1 Hox, Valerie A1 Gevaert, Philippe A1 Tomazic, Peter Valentin A1 Rondon, Carmen A1 Cingi, Cemal A1 Toppila-Salmi, Sanna A1 Karavelia, Aspasia A1 Bozkurt, Banu A1 Forster-Ruhrmann, Ulrike A1 Becker, Sven A1 Chaker, Adam M A1 Wollenberg, Barbara A1 Mosges, Ralph A1 Huppertz, Tilman A1 Hagemann, Jan A1 Bachert, Claus A1 Fokkens, Wytske K1 COVID-19 K1 CRSwNP K1 SARS-CoV-2 K1 Biologics K1 Chronic rhinosinusitis AB Chronic rhinosinusitis is regarded as a chronic airway disease. According to WHO recommendations, it may be a risk factor for COVID-19 patients. In most CRSwNP cases, the inflammatory changes affecting the nasal and paranasal mucous membranes are type-2 (T2) inflammation endotypes. The current knowledge on COVID-19 and on treatment options for CRS was analyzed by a literature search in Medline, Pubmed, international guidelines, the Cochrane Library and the Internet. Based on international literature, on current recommendations by WHO and other international organizations as well as on previous experience, a panel of experts from EAACI and ARIA provided recommendations for the treatment of CRS during the COVID-19 pandemic. Intranasal corticosteroids remain the standard treatment for CRS in patients with SARS-CoV-2 infection. Surgical treatments should be reduced to a minimum and surgery preserved for patients with local complications and for those with no other treatment options. Systemic corticosteroids should be avoided. Treatment with biologics can be continued with careful monitoring in noninfected patients and should be temporarily interrupted during the course of the COVID-19 infection. PB John Wiley and Sons YR 2021 FD 2021-03-06 LK http://hdl.handle.net/10668/16446 UL http://hdl.handle.net/10668/16446 LA en NO Klimek L, Jutel M, Bousquet J, Agache I, Akdis CA, Hox V, et al. Management of patients with chronic rhinosinusitis during the COVID-19 pandemic-An EAACI position paper. Allergy. 2021 Mar;76(3):677-688 DS RISalud RD Apr 20, 2025