RT Journal Article
T1 Cardiovascular assessment in liver transplant for non-alcoholic steatohepatitis patients: What we do, what we should do.
A1 Sanchez-Torrijos, Yolanda
A1 Ampuero, Javier
A1 Romero-Gomez, Manuel
K1 Cardiovascular risk
K1 Liver transplantation
K1 Non-alcoholic fatty liver disease
K1 Non-alcoholic steatohepatitis
K1 Pre-transplant assessment
AB Non-alcoholic fatty liver disease (NAFLD) is increasing considerably due to the current lifestyle, which means that it is becoming one of the main indications for liver transplantation. On the other hand, there is a strong association between NAFLD and cardiovascular disease. This has been evidenced in many studies revealing a higher presence of carotid plaques or carotid intima-media thickness, leading to cardiovascular events and, ultimately, mortality. According to the liver transplant guidelines, screening for heart disease in transplant candidates should be performed by electrocardiogram and transthoracic echocardiography while a stress echocardiogram should be reserved for those with more than two cardiovascular risk factors or greater than 50 years old. However, there are no specific recommendations in NAFLD patients requiring a liver transplantation, despite its well-known cardiovascular risk association. Many studies have shown that these patients probably require a more exhaustive assessment and a global approach including other specialists such as cardiologists or nutritionists. Also, the incidence of cardiovascular disease is also increased in NAFLD patients in the post-transplantation period in comparison with other etiologies, because of the pre-existent risk factors together with the immunosuppressive therapy. Therefore, an early intervention on the lifestyle and the individualized selection of the immunosuppressive regimen could lead to a modification of the cardiovascular risk factors in NAFLD patients requiring a liver transplantation.
PB Baishideng Publishing Group Co., Limited
SN 1948-5182
YR 2017
FD 2017-05-28
LK https://hdl.handle.net/10668/27905
UL https://hdl.handle.net/10668/27905
LA en
NO Sanchez-Torrijos Y, Ampuero J, Romero-Gómez M. Cardiovascular assessment in liver transplant for non-alcoholic steatohepatitis patients: What we do, what we should do. World J Hepatol. 2017 May 28;9(15):697-703.
DS RISalud
RD Apr 5, 2025