TY  - JOUR
AU  - Zheleva, Angelina
AU  - Camino, Lola P.
AU  - Fernandez-Fernandez, Nuria
AU  - Garcia-Rubio, Maria
AU  - Askjaer, Peter
AU  - Garcia-Muse, Tatiana
AU  - Aguilera, Andres
PY  - 2021
DO  - 10.1242/jcs.258435
SN  - 0021-9533
UR  - https://hdl.handle.net/10668/28365
T2  - Journal of cell science
AB  - Transcription is an essential process of DNA metabolism, yet it makes DNA more susceptible to DNA damage. THSC/TREX-2 is a conserved eukaryotic protein complex with a key role in mRNP biogenesis and maturation that prevents genome instability. One...
LA  - en
PB  - Company biologists ltd
KW  - C. elegans
KW  - THSC/TREX-2 complex
KW  - replication
KW  - DNA-RNA hybrids
KW  - genome instability
KW  - Messenger-rna export
KW  - R-loops
KW  - Meiotic recombination
KW  - Trex-2 complex
KW  - Transcription
KW  - Protein
KW  - Brca2
KW  - Yeast
KW  - Tho
KW  - Impairment
TI  - C. elegans THSC/TREX-2 deficiency causes replication stress and genome instability
TY  - research article
VL  - 134
ER  -