TY - JOUR AU - Lopez-Millan, Belen AU - Costales, Paula AU - Gutiérrez-Agüera, Francisco AU - Díaz de la Guardia, Rafael AU - Roca-Ho, Heleia AU - Vinyoles, Meritxell AU - Rubio-Gayarre, Alba AU - Safi, Rémi AU - Castaño, Julio AU - Romecín, Paola Alejandra AU - Ramírez-Orellana, Manuel AU - Anguita, Eduardo AU - Jeremias, Irmela AU - Zamora, Lurdes AU - Rodríguez-Manzaneque, Juan Carlos AU - Bueno, Clara AU - Morís, Francisco AU - Menendez, Pablo PY - 2022 DO - 10.3390/cancers14061593 SN - 2072-6694 UR - http://hdl.handle.net/10668/20880 T2 - Cancers AB - Acute myeloid leukemia (AML) is the most common acute leukemia in adults. Patients with AML harboring a constitutively active internal tandem duplication mutation (ITDMUT) in the FMS-like kinase tyrosine kinase (FLT3) receptor generally have a poor... LA - en KW - AML KW - AML preclinical model KW - EC-70124 multi-kinase inhibitor KW - FLT3 inhibitor KW - FLT3-ITD mutation TI - The Multi-Kinase Inhibitor EC-70124 Is a Promising Candidate for the Treatment of FLT3-ITD-Positive Acute Myeloid Leukemia. TY - research article VL - 14 ER -