TY - JOUR AU - De Laurentiis, Michelino AU - Borstnar, Simona AU - Campone, Mario AU - Warner, Ellen AU - Bofill, Javier Salvador AU - Jacot, William AU - Dent, Susan AU - Martin, Miguel AU - Ring, Alistair AU - Cottu, Paul AU - Lu, Janice AU - Ciruelos, Eva AU - Azim, Hamdy A AU - Chatterjee, Sanjoy AU - Zhou, Katie AU - Wu, Jiwen AU - Menon-Singh, Lakshmi AU - Zamagni, Claudio PY - 2021 DO - 10.1007/s10549-021-06334-0 UR - http://hdl.handle.net/10668/18396 T2 - Breast cancer research and treatment AB - CompLEEment-1 is a phase 3b trial in an expanded patient population with hormone receptor-positive (HR +), human epidermal growth factor receptor-2-negative (HER2-) advanced breast cancer (ABC), the largest current trial of cyclin-dependent kinase 4... LA - en KW - Advanced breast cancer KW - CDK4/6 inhibitor KW - Endocrine therapy KW - Ribociclib KW - Aminopyridines KW - Antineoplastic Combined Chemotherapy Protocols KW - Breast Neoplasms KW - Female KW - Humans KW - Letrozole KW - Purines KW - Quality of Life KW - Receptor, ErbB-2 KW - Receptors, Estrogen KW - Receptors, Progesterone TI - Full population results from the core phase of CompLEEment-1, a phase 3b study of ribociclib plus letrozole as first-line therapy for advanced breast cancer in an expanded population. TY - research article VL - 189 ER -