TY  - JOUR
AU  - Mellado-Gil, José Manuel
AU  - Jiménez-Moreno, Carmen María
AU  - Martin-Montalvo, Alejandro
AU  - Alvarez-Mercado, Ana Isabel
AU  - Fuente-Martin, Esther
AU  - Cobo-Vuilleumier, Nadia
AU  - Lorenzo, Petra Isabel
AU  - Bru-Tari, Eva
AU  - Herrera-Gómez, Irene de Gracia
AU  - López-Noriega, Livia
AU  - Pérez-Florido, Javier
AU  - Santoyo-López, Javier
AU  - Spyrantis, Andreas
AU  - Meda, Paolo
AU  - Boehm, Bernhard O
AU  - Quesada, Ivan
AU  - Gauthier, Benoit R
PY  - 2016
DO  - 10.1007/s00125-016-3864-0
UR  - http://hdl.handle.net/10668/9776
T2  - Diabetologia
AB  - A strategy to enhance pancreatic islet functional beta cell mass (BCM) while restraining inflammation, through the manipulation of molecular and cellular targets, would provide a means to counteract the deteriorating glycaemic control associated with...
LA  - en
KW  - Beta cell degeneration
KW  - ER homeostasis
KW  - PAX4
KW  - RIP-B7.1
KW  - Type 1 diabetes
KW  - Animals
KW  - Apoptosis
KW  - Cell Proliferation
KW  - Diabetes Mellitus, Type 1
KW  - Endoplasmic Reticulum
KW  - Female
KW  - Homeodomain Proteins
KW  - Insulin-Secreting Cells
KW  - Male
KW  - Mice
KW  - Mice, Mutant Strains
KW  - Paired Box Transcription Factors
TI  - PAX4 preserves endoplasmic reticulum integrity preventing beta cell degeneration in a mouse model of type 1 diabetes mellitus.
TY  - research article
VL  - 59
ER  -