TY  - JOUR
AU  - Balestra, Fernando R.
AU  - Domínguez-Calvo, Andrés
AU  - Wolf, Benita
AU  - Busso, Coralie
AU  - Buff, Alizée
AU  - Averink, Tessa
AU  - Lipsanen-Nyman, Marita
AU  - Huertas, Pablo
AU  - Ríos, Rosa M.
AU  - Gönczy, Pierre
PY  - 2021
DO  - 10.7554/eLife.62640
UR  - http://hdl.handle.net/10668/3984
T2  - eLife
AB  - TRIM37 is an E3 ubiquitin ligase mutated in Mulibrey nanism, a disease with impaired organ growth and increased tumor formation. TRIM37 depletion from tissue culture cells results in supernumerary foci bearing the centriolar protein Centrin. Here, we...
LA  - en
KW  - Cells
KW  - Mulibrey nanism
KW  - E3 ubiquitin ligase
KW  - Centrioles
KW  - Enzymes
KW  - Células
KW  - Enanismo mulibrey
KW  - Ubiquitina-proteína ligasas
KW  - Centriolos
KW  - Enzimas
KW  - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Cycle
KW  - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Lineage
KW  - Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Cytoskeleton::Microtubule-Organizing Center::Centrosome::Centrioles
KW  - Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Cell Line::Cell Line, Tumor::HeLa Cells
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Cytoskeleton::Microtubule-Organizing Center
KW  - Medical Subject Headings::Diseases::Congenital, Hereditary, and Neonatal Diseases and Abnormalities::Genetic Diseases, Inborn::Dwarfism::Mulibrey Nanism
KW  - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Ligases::Ubiquitin-Protein Ligase Complexes::Ubiquitin-Protein Ligases
TI  - TRIM37 prevents formation of centriolar protein assemblies by regulating Centrobin
TY  - research article
ER  -