RT Journal Article T1 Health-related quality of life in caregivers of patients with Alzheimer's disease. T2 Calidad de vida relacionada con la salud en cuidadores de pacientes con enfermedad de Alzheimer. A1 Garzón-Maldonado, F J A1 Gutiérrez-Bedmar, M A1 García-Casares, N A1 Pérez-Errázquin, F A1 Gallardo-Tur, A A1 Martínez-Valle Torres, M D K1 Alzheimer's disease K1 Calidad de vida relacionada con la salud K1 Cuestionario K1 Cuidador informal K1 Dementia Unit K1 Enfermedad de Alzheimer K1 Health-related quality of life K1 Informal caregiver K1 Questionnaire K1 SF-36 K1 Unidad de Demencias AB Informal caregivers of patients with Alzheimer's disease (AD) have a poor health-related quality of life (HRQOL). HRQOL is an increasingly common user-focused outcome measure. We have evaluated HRQOL longitudinally in caregivers of AD patients at baseline and at 12 months. Ninety-seven patients diagnosed with AD according to the NINCDS-ADRDA (National Institute of Neurological and Communicative Disorders and Stroke, and Alzheimer's Disease and Related Disorders Association) and their 97 respective primary caregivers were included in the study. We analysed the following data at the baseline visit: sociodemographic data of both patients and carers, patients' clinical variables, and data related to the healthcare provided to patients by carers. HRQOL of caregivers was measured with the SF-36 questionnaire at baseline and 12 months later. At 12 months, primary caregivers scored lower in the 8 subscales of the SF-36 questionnaire; differences were statistically significant in all dimensions except for 'physical function' and 'social function'. Baseline scores in our sample were lower than those of the general population. 'Vitality' is the dimension that presented the lowest scores. HRQOL in caregivers of patients with Alzheimer's disease deteriorates over time and is poorer than that of the age- and sex-matched general population. YR 2016 FD 2016-04-25 LK http://hdl.handle.net/10668/10037 UL http://hdl.handle.net/10668/10037 LA en LA es DS RISalud RD Apr 7, 2025