RT Journal Article T1 Decision Making Impairment: A Shared Vulnerability in Obesity, Gambling Disorder and Substance Use Disorders? A1 Mallorqui-Bague, Nuria A1 Fagundo, Ana B. A1 Jimenez-Murcia, Susana A1 de la Torre, Rafael A1 Banos, Rosa M. A1 Botella, Cristina A1 Casanueva, Felipe F. A1 Crujeiras, Ana B. A1 Fernandez-Garcia, Jose C. A1 Fernandez-Real, Jose M. A1 Fruhbeck, Gema A1 Granero, Roser A1 Rodriguez, Amaia A1 Tolosa-Sola, Iris A1 Ortega, Francisco J. A1 Tinahones, Francisco J. A1 Alvarez-Moya, Eva A1 Ochoa, Cristian A1 Menchon, Jose M. A1 Fernandez-Aranda, Fernando K1 Ventromedial prefrontal cortex K1 Food addiction K1 Deficits K1 Alcohol K1 Abusers K1 Task K1 Sex AB IntroductionAddictions are associated with decision making impairments. The present study explores decision making in Substance use disorder (SUD), Gambling disorder (GD) and Obesity (OB) when assessed by Iowa Gambling Task (IGT) and compares them with healthy controls (HC).MethodsFor the aims of this study, 591 participants (194 HC, 178 GD, 113 OB, 106 SUD) were assessed according to DSM criteria, completed a sociodemographic interview and conducted the IGT.ResultsSUD, GD and OB present impaired decision making when compared to the HC in the overall task and task learning, however no differences are found for the overall performance in the IGT among the clinical groups. Results also reveal some specific learning across the task patterns within the clinical groups: OB maintains negative scores until the third set where learning starts but with a less extend to HC, SUD presents an early learning followed by a progressive although slow improvement and GD presents more random choices with no learning.ConclusionsDecision making impairments are present in the studied clinical samples and they display individual differences in the task learning. Results can help understanding the underlying mechanisms of OB and addiction behaviors as well as improve current clinical treatments. PB Public library science SN 1932-6203 YR 2016 FD 2016-09-30 LK http://hdl.handle.net/10668/19162 UL http://hdl.handle.net/10668/19162 LA en DS RISalud RD Apr 17, 2025