TY - JOUR AU - Van Cutsem, Eric AU - Martinelli, Erika AU - Cascinu, Stefano AU - Sobrero, Alberto AU - Banzi, Maria AU - Seitz, Jean-François AU - Barone, Carlo AU - Ychou, Marc AU - Peeters, Marc AU - Brenner, Baruch AU - Hofheinz, Ralf Dieter AU - Maiello, Evaristo AU - André, Thierry AU - Spallanzani, Andrea AU - Garcia-Carbonero, Rocio AU - Arriaga, Yull E AU - Verma, Udit AU - Grothey, Axel AU - Kappeler, Christian AU - Miriyala, Ashok AU - Kalmus, Joachim AU - Falcone, Alfredo AU - Zaniboni, Alberto PY - 2018 DO - 10.1634/theoncologist.2018-0072 UR - http://hdl.handle.net/10668/12916 T2 - The oncologist AB - In the phase III CORRECT trial, regorafenib significantly improved survival in treatment-refractory metastatic colorectal cancer (mCRC). The CONSIGN study was designed to further characterize regorafenib safety and allow patients access to regorafenib... LA - en KW - Metastatic colorectal cancer KW - Prospective studies KW - Regorafenib KW - Toxicities KW - Adult KW - Aged KW - Aged, 80 and over KW - Colorectal Neoplasms KW - Disease Progression KW - Female KW - Humans KW - Male KW - Middle Aged KW - Neoplasm Metastasis KW - Phenylurea Compounds KW - Prospective Studies KW - Pyridines TI - Regorafenib for Patients with Metastatic Colorectal Cancer Who Progressed After Standard Therapy: Results of the Large, Single-Arm, Open-Label Phase IIIb CONSIGN Study. TY - research article VL - 24 ER -