TY - JOUR AU - Castro, Isabel AU - Sampaio-Marques, Belém AU - Areias, Anabela C. AU - Sousa, Hugo AU - Fernandes, Ângela AU - Sanchez-Maldonado, José Manuel AU - Cunha, Cristina AU - Carvalho, Agostinho AU - Sainz, Juan AU - Ludovico, Paula PY - 2021 DO - 10.3390/cancers13061344 UR - http://hdl.handle.net/10668/4281 T2 - Cancers AB - Acute myeloid leukemia (AML) is the most common acute leukemia, characterized by a heterogeneous genetic landscape contributing, among others, to the occurrence of metabolic reprogramming. Autophagy, a key player on metabolism, plays an essential role... LA - en PB - MDPI KW - Acute myeloid leukemia KW - ATG10 KW - Autophagy KW - Single nucleotide polymorphism KW - Clonal hematopoiesis KW - Leucemia mieloide aguda KW - Autofagia KW - Polimorfismo de nucleótido simple KW - Hematopoyesis clonal KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Persons::Persons::Age Groups::Adult::Aged KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Polymorphism, Genetic::Polymorphism, Single Nucleotide KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Alleles KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Odds Ratio KW - Medical Subject Headings::Anatomy::Hemic and Immune Systems::Blood::Blood Cells::Leukocytes::Leukocytes, Mononuclear KW - Medical Subject Headings::Persons::Persons::Volunteers::Healthy Volunteers KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Models, Theoretical::Models, Statistical::Logistic Models KW - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Histologic Type::Leukemia::Leukemia, Myeloid::Leukemia, Myeloid, Acute KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factors KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death::Autophagy TI - Functional Genetic Variants in ATG10 Are Associated with Acute Myeloid Leukemia TY - research article ER -