TY - JOUR AU - Tejada, Miguel A AU - Montilla-Garcia, Angeles AU - Gonzalez-Cano, Rafael AU - Bravo-Caparros, Inmaculada AU - Ruiz-Cantero, M Carmen AU - Nieto, Francisco R AU - Cobos, Enrique J PY - 2018 DO - 10.1016/j.phrs.2018.02.008 UR - http://hdl.handle.net/10668/12150 T2 - Pharmacological research AB - Immune cells have a known role in pronociception, since they release a myriad of inflammatory algogens which interact with neurons to facilitate pain signaling. However, these cells also produce endogenous opioid peptides with analgesic potential. The... LA - en PB - Elsevier Ltd KW - Analgesia KW - Endogenous opioid peptides KW - Immune cells KW - Neuro-immune interactions KW - Sigma-1 receptors KW - Analgesia KW - Analgesics, Opioid KW - Animals KW - Humans KW - Inflammation KW - Molecular Targeted Therapy KW - Pain KW - Receptors, sigma TI - Targeting immune-driven opioid analgesia by sigma-1 receptors: Opening the door to novel perspectives for the analgesic use of sigma-1 antagonists. TY - research article VL - 131 ER -