RT Journal Article
T1 Growth Hormone and Endometrial Receptivity.
A1 Altmäe, Signe
A1 Aghajanova, Lusine
K1 endometrial receptivity
K1 endometrium
K1 growth hormone
K1 in vitro fertilization
K1 infertility
K1 transcriptome
AB Administration of growth hormone (GH) during ovarian stimulation has shown beneficial effects on in vitro fertilization (IVF) outcomes. It is generally believed that this improvement is due to the stimulating effect of GH on oocyte quality. However, studies are emerging that show possible positive effect of GH administration on endometrial receptivity, thus suggesting an additional potential benefit at the level of the uterus, especially among women with recurrent implantation failure, thin endometrium, and older normal responders. This review summarizes recent data on GH co-treatment effects on endometrium and endometrial receptivity among infertile women undergoing IVF, and proposes possible mechanisms of GH actions in the endometrium.
PB Frontiers Research Foundation
SN 1664-2392
YR 2019
FD 2019-09-09
LK http://hdl.handle.net/10668/14845
UL http://hdl.handle.net/10668/14845
LA en
NO Altmäe S, Aghajanova L. Growth Hormone and Endometrial Receptivity. Front Endocrinol (Lausanne). 2019 Sep 24;10:11.
NO This study was supported by the University of Granada Plan Propio de Investigación 2016–Excellence actions: Unit of Excellence on Exercise and Health (UCEES)–and Plan Propio de Investigación 2018–Programa Contratos-Puente, and the Junta de Andalucía, Consejería de Conocimiento, Investigación y Universidades, European Regional Development Funds (ref. SOMM17/6107/UGR); and the Spanish Ministry of Economy, Industry and Competitiveness (MINECO), and European Regional Development Fund (FEDER): grants RYC-2016-21199 and ENDORE SAF2017-87526.
DS RISalud
RD Mar 14, 2025