RT Journal Article T1 New insights to occult gastrointestinal bleeding: From pathophysiology to therapeutics. A1 Sánchez-Capilla, Antonio Damián A1 Torre-Rubio, Paloma De La A1 Redondo-Cerezo, Eduardo K1 Obscure gastrointestinal bleeding K1 Angiodysplasia K1 Wireless capsule endoscopy K1 Double balloon enteroscopy K1 Endoscopía Gastrointestinal K1 Hemorragia Gastrointestinal K1 Endoscopía Capsular K1 Angiodisplasia K1 Enteroscopía de Doble Balón AB Obscure gastrointestinal bleeding is still a clinical challenge for gastroenterologists. The recent development of novel technologies for the diagnosis and treatment of different bleeding causes has allowed a better management of patients, but it also determines the need of a deeper comprehension of pathophysiology and the analysis of local expertise in order to develop a rational management algorithm. Obscure gastrointestinal bleeding can be divided in occult, when a positive occult blood fecal test is the main manifestation, and overt, when external sings of bleeding are visible. In this paper we are going to focus on overt gastrointestinal bleeding, describing the physiopathology of the most usual causes, analyzing the diagnostic procedures available, from the most classical to the novel ones, and establishing a standard algorithm which can be adapted depending on the local expertise or availability. Finally, we will review the main therapeutic options for this complex and not so uncommon clinical problem. PB Baishideng Publishing Group YR 2014 FD 2014-08-15 LK http://hdl.handle.net/10668/1866 UL http://hdl.handle.net/10668/1866 LA en NO Sánchez-Capilla AD, Torre-Rubio P De La, Redondo-Cerezo E. New insights to occult gastrointestinal bleeding: From pathophysiology to therapeutics. World J Gastrointest Pathophysiol. 2014 ; 5(3):271-83 NO Journal Article; Review; DS RISalud RD Apr 6, 2025