TY - JOUR AU - Anguita-Ruiz, Augusto AU - Pastor-Villaescusa, Belen AU - Leis, Rosaura AU - Bueno, Gloria AU - Hoyos, Raul AU - Vazquez-Cobela, Rocio AU - Latorre-Millan, Miriam AU - Cañete, M Dolores AU - Caballero-Villarraso, Javier AU - Gil, Angel AU - Cañete, Ramon AU - Aguilera, Concepcion M PY - 2019 DO - 10.3390/jcm8091471 SN - 2077-0383 UR - http://hdl.handle.net/10668/14511 T2 - Journal of clinical medicine AB - Metformin is a first-line oral antidiabetic agent that has shown additional effects in treating obesity and metabolic syndrome. Inter-individual variability in metformin response could be partially explained by the genetic component. Here, we aimed to... LA - en PB - MDPI KW - SNP KW - Clinical trials KW - Metformin KW - Obesity KW - Pediatrics KW - Pharmacogenetics KW - Hypoglycemic agents KW - Metformin KW - Body mass index KW - Pediatric obesity KW - Metabolic syndrome KW - Pharmacogenetics KW - Genotype KW - Lipids TI - Common Variants in 22 Genes Regulate Response to Metformin Intervention in Children with Obesity: A Pharmacogenetic Study of a Randomized Controlled Trial. TY - research article VL - 8 ER -