TY - JOUR AU - Roa, Juan AU - Barroso, Alexia AU - Ruiz-Pino, Francisco AU - Vazquez, Maria Jesus AU - Seoane-Collazo, Patricia AU - Martinez-Sanchez, Noelia AU - Garcia-Galiano, David AU - Ilhan, Tuncay AU - Pineda, Rafael AU - Leon, Silvia AU - Manfredi-Lozano, Maria AU - Heras, Violeta AU - Poutanen, Matti AU - Castellano, Juan M AU - Gaytan, Francisco AU - Dieguez, Carlos AU - Pinilla, Leonor AU - Lopez, Miguel AU - Tena-Sempere, Manuel PY - 2018 DO - 10.1073/pnas.1802053115 UR - http://hdl.handle.net/10668/13119 T2 - Proceedings of the National Academy of Sciences of the United States of America AB - Conditions of metabolic distress, from malnutrition to obesity, impact, via as yet ill-defined mechanisms, the timing of puberty, whose alterations can hamper later cardiometabolic health and even life expectancy. AMP-activated protein kinase (AMPK),... LA - en PB - National Academy of Sciences KW - AMPK KW - Kiss1 KW - Energy balance KW - Puberty KW - Undernutrition KW - AMP-activated protein kinases KW - Aminoimidazole carboxamide KW - Animals KW - Animals, genetically modified KW - Arcuate nucleus of hypothalamus KW - Caloric restriction KW - Estradiol KW - Female KW - Gene expression regulation, developmental KW - Kisspeptins KW - Luteinizing hormone KW - Malnutrition KW - Mice KW - Mice, inbred C57BL KW - Neurons KW - Rats KW - Rats, wistar KW - Ribonucleotides KW - Sexual maturation KW - Signal transduction KW - Time factors TI - Metabolic regulation of female puberty via hypothalamic AMPK-kisspeptin signaling. TY - research article VL - 115 ER -