RT Journal Article
T1 How Does Vaccination against SARS-CoV-2 Affect Hospitalized Patients with COVID-19?
A1 Moreno-Nunez, Paloma
A1 Bueno-Cavanillas, Aurora
A1 San Jose-Saras, Diego
A1 Vicente-Guijarro, Jorge
A1 Fernandez Chavez, Abelardo Claudio
A1 Aranaz-Andres, Jesus Maria
K1 COVID-19 vaccines
K1 critical care
K1 hospital mortality
K1 hospitalisation
K1 vaccine effectiveness
AB (1) Background: The development of effective COVID-19 vaccines has reduced the impact of COVID-19 on the general population. Our study aims to analyze how vaccination modifies the likelihood of death and length of stay in hospitalized patients with COVID-19; (2) Methods: A retrospective cohort study of 1927 hospitalized patients infected with COVID-19 was conducted. Information was gathered on vaccination status, hospitalization episode, and clinical profile of the patients. The effect of vaccination on mortality was analyzed using a multiple logistic regression model, and length of stay was analyzed using linear regression. The performance and fit of the models were evaluated; (3) Results: In hospitalized patients with COVID-19, the risk of dying during admission in vaccinated patients was half that of non-vaccinated (OR: 0.45; CI 95%: 0.25 to 0.84). In patients who were discharged due to improvement, the reduction in hospital stay in vaccinated patients was 3.17 days (CI 95%: 5.88 to 0.47); (4) Conclusions: Patients who, despite having been vaccinated, acquire the infection by SARS-CoV-2, have a significant reduction of the risk of death during admission and a reduction of hospital stay compared with unvaccinated patients.
PB MDPI AG
SN 2077-0383
YR 2022
FD 2022-07-05
LK http://hdl.handle.net/10668/21317
UL http://hdl.handle.net/10668/21317
LA en
DS RISalud
RD Apr 8, 2025