%0 Journal Article
%A Moreno-Nunez, Paloma
%A Bueno-Cavanillas, Aurora
%A San Jose-Saras, Diego
%A Vicente-Guijarro, Jorge
%A Fernandez Chavez, Abelardo Claudio
%A Aranaz-Andres, Jesus Maria
%T How Does Vaccination against SARS-CoV-2 Affect Hospitalized Patients with COVID-19?
%D 2022
%@ 2077-0383
%U http://hdl.handle.net/10668/21317
%X (1) Background: The development of effective COVID-19 vaccines has reduced the impact of COVID-19 on the general population. Our study aims to analyze how vaccination modifies the likelihood of death and length of stay in hospitalized patients with COVID-19; (2) Methods: A retrospective cohort study of 1927 hospitalized patients infected with COVID-19 was conducted. Information was gathered on vaccination status, hospitalization episode, and clinical profile of the patients. The effect of vaccination on mortality was analyzed using a multiple logistic regression model, and length of stay was analyzed using linear regression. The performance and fit of the models were evaluated; (3) Results: In hospitalized patients with COVID-19, the risk of dying during admission in vaccinated patients was half that of non-vaccinated (OR: 0.45; CI 95%: 0.25 to 0.84). In patients who were discharged due to improvement, the reduction in hospital stay in vaccinated patients was 3.17 days (CI 95%: 5.88 to 0.47); (4) Conclusions: Patients who, despite having been vaccinated, acquire the infection by SARS-CoV-2, have a significant reduction of the risk of death during admission and a reduction of hospital stay compared with unvaccinated patients.
%K COVID-19 vaccines
%K critical care
%K hospital mortality
%K hospitalisation
%K vaccine effectiveness
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