TY - JOUR AU - Geribaldi-Doldán, Noelia AU - Hervás-Corpión, Irati AU - Gómez-Oliva, Ricardo AU - Domínguez-García, Samuel AU - Ruiz, Félix A. AU - Iglesias-Lozano, Irene AU - Carrascal, Livia AU - Pardillo-Díaz, Ricardo AU - Gil-Salú, José L. AU - Nunez-Abades, Pedro AU - Valor, Luis M. AU - Castro, Carmen PY - 2021 DO - 10.3390/biomedicines9040381 UR - http://hdl.handle.net/10668/4420 T2 - Biomedicines AB - Glioblastoma (GBM) is the most frequent and aggressive primary brain tumor and is associated with a poor prognosis. Despite the use of combined treatment approaches, recurrence is almost inevitable and survival longer than 14 or 15 months after... LA - en PB - MDPI KW - Glioblastoma KW - Protein kinase C KW - Glioma stem cells KW - Neurogenesis KW - Neural stem cells KW - Temozolomide KW - Enzastaurin KW - Epidermal growth factor receptor KW - Neuregulin KW - Brain tumor KW - Apoptosis KW - Cell cycle KW - Proteína quinasa C KW - Células madre KW - Neurogénesis KW - Células-madre neurales KW - Temozolomida KW - Receptores ErbB KW - Neurregulinas KW - Neoplasias encefálicas KW - Ciclo celular KW - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Histologic Type::Neoplasms, Germ Cell and Embryonal::Neuroectodermal Tumors::Neoplasms, Neuroepithelial::Glioma::Astrocytoma::Glioblastoma KW - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Isoenzymes KW - Medical Subject Headings::Diseases::Nervous System Diseases::Central Nervous System Diseases::Brain Diseases::Brain Neoplasms KW - Medical Subject Headings::Anatomy::Cells::Stem Cells::Neoplastic Stem Cells KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death::Apoptosis KW - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Phosphotransferases::Phosphotransferases (Alcohol Group Acceptor)::Protein Kinases::Protein-Serine-Threonine Kinases::Protein Kinase C KW - Medical Subject Headings::Anatomy::Cells::Stem Cells::Neural Stem Cells KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Cycle KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans TI - Targeting Protein Kinase C in Glioblastoma Treatment TY - review article ER -