%0 Journal Article
%A Rodríguez-Capitán, Jorge
%A Sánchez-Pérez, Andrés
%A Ballesteros-Pradas, Sara
%A Millán-Gómez, Mercedes
%A Cardenal-Piris, Rosa
%A Oneto-Fernández, Manuel
%A Gutiérrez-Alonso, Lola
%A Rivera-López, Ricardo
%A Guisado-Rasco, Agustín
%A Cano-García, Macarena
%A Gutiérrez-Bedmar, Mario
%A Jiménez-Navarro, Manuel
%T Prognostic Implication of Non-Obstructive Coronary Lesions: A New Classification in Different Settings.
%D 2021
%@ 2077-0383
%U https://hdl.handle.net/10668/27187
%X The clinical significance of non-obstructive coronary artery disease is the subject of debate. Our objective was to evaluate the long-term cardiovascular prognosis associated with non-obstructive coronary artery disease in patients undergoing coronary angiography, and to conduct a stratification by sex, diabetes, and clinical indication. We designed a multi-centre retrospective longitudinal observational study of 3265 patients that were classified into three groups: normal coronary arteries (lesion 70%, 1196 patients). During a mean follow-up of 43 months, we evaluated a combined cardiovascular event: acute myocardial infarction, stroke, hospitalization for heart failure, or cardiovascular death. Multivariable-adjusted Cox proportional hazard models showed a worse prognosis in patients with non-obstructive coronary artery disease, in comparison with patients of normal coronary arteries group, in the total population (hazard ratio 1.72, 95% confidence interval 1.23-2.39; p for trend
%K acute coronary syndrome
%K coronary angiography
%K coronary artery disease
%K diabetes mellitus
%K sex
%~